This presentation examines the in silico prediction of ADME (Absorption, Distribution, Metabolism, and Excretion) parameters for pure compounds isolated from the antibacterial plants Strychnos johnsonii, Helichrysum foetidum, and Helichrysum mechowianum. It identifies potential lead compounds, including Apigenin-7-O-β-D-Glucoside and 10,11-Na-methyl-β-carboline, for developing treatments against bacterial meningitis. Using computational models, the study evaluates drug-likeness and pharmacokinetic properties, emphasizing their importance in early drug development stages. The document features graphical representations of molecular structures and analysis results, along with detailed experimental methods and computational approaches.