This document outlines key milestones and strategies for implementing traditional medicine (TM) in the WHO African Region since 2000. The initial strategy focused on integrating TM into health systems through policy development, capacity building, intellectual property protection, research, and local production. Key declarations, such as the Algiers and Ouagadougou Declarations (2008), highlighted research and access to essential medicines. By 2020, progress reports assessed successes, challenges, and set priorities for a third decade (2021-2030) to further integrate TM. Key areas include policy and regulation, community and resource mobilization, local production, research, and public health system integration.