(((pt:"ensaio clinico fase I" or pt:"ensaio clinico fase II" or pt:"ensaio clinico fase III" or (tw:"clinical trial" and tw:phase$ and (tw:one or tw:three or tw:two or tw:I or tw:II or tw:III)) or mh:"avaliacao pre-clinica de medicamentos" or mh:"Relação Dose-Resposta a Droga" or (tw:"double blind" and tw:trial) or ((tw:sequential or tw:stratified) and tw:trial) or ((tw:diagnostic$ or tw:drug$ or SH:"uso terapeutico" or SH:quimioterapia or tw:product$ or tw:vaccine$ or tw:clinical) and (tw:test$ or tw:development or SH:"isolamento & purificacao")) or tw:randomized$ or tw:crossover or tw:"cross-over" or tw:pharmaco$ or ((tw:minimal or tw:maximal or tw:lethal or tw:toxic or tw:therapeutic$) and tw:dose) or mh:"efeito placebo" or tw:"placebo effect") and mh:humanos) and not mh:animais)
iAH search strategy
(pt ensaio clinico fase I or pt ensaio clinico fase II or pt ensaio clinico fase III or (tw clinical and tw trial and tw phase and (tw one or tw three or tw two)) or mh avaliacao pre-clinica de medicamentos or mh Relação Dose-Resposta a Droga or (tw double and tw blind and tw trial) or ((tw sequential or tw stratified) and tw trial) or ((tw diagnostic$ or tw drug$ or mh /tu or mh /dt or tw product$ or tw vaccine$ or tw clinical) and (tw test$ or development or mh /ip)) or tw randomized$ or tw crossover or (tw cross and tw over) or tw pharmaco$ or ((tw minimal or tw maximal or tw lethal or tw toxic or tw therapeutic) and tw dose) or mh efeito placebo or (tw placebo and tw effect)) and ct humanos and not ct animais